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Product description

About Us:
Mishansha has a professional team and devotes ourselves to the research and development, design and manufacturing of shoes.
To meet the needs of different customers,we constantly creating new series of women'and men'winter boots,snow boots,home slippers,water shoes,outdoor slippers etc.
Mishansha, idea of "Customer First and Products First",it just want to make people more and more easier to enjoy their spring, summer, autumn and winter .
In the winter of 2018 years, our company focused on creating the series of winter boots.
These winter boots are the result of our Ramp;D team using one year's time based on various experiments.Ergonomic design is adopted to ensure beautiful lines and comfortable feet feeling.Rubber sole composition is designed to be more non-slip and has achieved better protection of your feet."br"With fine fluffy wool lining from top to insole,this snows boots offer you ultimate suitable for your childin."br"Besides,the winter boots can be easily paired with jeans, slacks, etc.When you go to vacation, skiing,walking the dog,walking,taking the express,indoor,leisure,fishing,long airline flight,around the house,get the paper,grab something from the car,run a quick errand,running up to the little store etc.Him can easily wear Mishansha snow boots to solve these problems."br""b"Mishansha snow boots main features:"br"Has a nice grip to prevent slipping"br"Lightweight,soft and comfortable "br"Waterproof"br"Warm inside"br"Give your child a wonderful gift"br""b"NOTE:"br"Our snow boots are sold worldwide, so when you receive our product, your country’s shoes sizing info will be displayed, as well as sizing info for other countries. We’re confident that our shoes will fit you well."br"Thank you for your trust in Mishansha winter boots. At the same time we hope that you can give us some valuable advice and make us do better.

Girls Boys Toddler/Little Kid/Big Kid Winter Snow Boots Warm Wat

CURRENT ISSUE
September, 2021

No. 106 (9)

2020 Impact Factor: 9.941 Submission > Acceptance: 52 days
ARTICLES IN THREE SENTENCES
Article

Long-term outcomes from the phase II L-MIND study of tafasitamab (MOR208) plus lenalidomide in patients with relapsed or refractory diffuse large B-cell lymphoma

This open-label, single-arm study investigated the long-term efficacy of tafasitamab plus lenalidomide in 81 patients with relapsed/refractory diffuse large B-cell lymphoma. The response rate was 57.5%, including complete responses in 40.0% of patients, and the median duration of response was 43.9 months. This treatment is a valuable option for patients not eligible for autologous stem-cell transplantation.

Johannes Duell et al.

Case Report

Clinical genomic profiling of novel grey zone lymphoma paired lesions with sequential central nervous system involvement in two adolescent patients

Grey zone lymphoma is a B-cell lymphoma, unclassifiable, with features intermediate between those of large B-cell lymphoma and classic Hodgkin lymphoma. The in-depth study of the two adolescent patients described in this case report expands the clinicopathological and genomic spectrum of this rare pediatric disease. Moreover, it provides information on their response to treatment.

Cagla Y. Benkli et al.

Article

CAMT-MPL: congenital amegakaryocytic thrombocytopenia caused by MPL mutations - heterogeneity of a monogenic disorder - a comprehensive analysis of 56 patients

The clinical picture of 56 patients with congenital amegakaryocytic thrombocytopenia due to MPL mutations was much more varied than previously thought. Twenty-five per cent of them had no signs of thrombocytopenia at birth, and 50% had non-hematologic defects. Pancytopenia developed in (nearly) all patients and hematopoietic stem-cell transplantation was effective in 87% of cases.

Manuela Germeshausen et al.

Article

Oxidative stress activates red cell adhesion to laminin in sickle cell disease

Sickle red blood cells exhibit abnormal adhesion to laminin mediated by Lu/BCAM protein at their surface. This study provides evidence of the involvement of oxidative stress in post-translational modifications of Lu/BCAM which impact the protein’s distribution and cis-interaction with glycophorin C at the cell surface activating its adhesive function in dense sickle red cells. The authors speculate that antioxidant drugs might attenuate this phenomenon.

Maria Alejandra Lizarralde-Iragorri et al.

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